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Updated: May 4, 2026

Using Fluorescent Proteins to Monitor Glycosome Dynamics in the African Trypanosome
Published on: August 19, 2014
Green fluorescent diamidines as diagnostic probes for trypanosomes
Federica Giordani1, Manoj Munde, W David Wilson
1Department of Chemistry, Georgia State University, Atlanta, Georgia, USA.
Abstract:
Light-emitting diode (LED) fluorescence microscopy offers potential benefits in the diagnosis of human African trypanosomiasis and in other aspects of diseases management, such as detection of drug-resistant strains. To advance such approaches, reliable and specific fluorescent markers to stain parasites in human fluids are needed. Here we describe a series of novel green fluorescent diamidines and their suitability as probes with which to stain trypanosomes.
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