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Rapid development of IRIS in the form of cryptococcal meningitis after beginning ART
Abida Malik1, Parvez A Khan1, Fatima Shujatullah1
1Department of Microbiology, J.N. Medical College and Hospital, A.M.U., Aligarh 202002, India.
Abstract:
Around one fourth of patients infected with human immunodeficiency virus (HIV) and given antiretroviral therapy (ART) experience inflammatory or cellular proliferative disease associated with a preexisting opportunistic infection. Many such infections are subclinical or quiescent before the patient begins ART. Cryptococcal immune reconstitution inflammatory syndrome may present as a clinical deterioration or new presentation of cryptococcal disease following initiation of antiretroviral therapy (ART) and is believed to be caused by recovery of Cryptococcus-specific immune responses. In the following report we present a case of expeditious developed IRIS in the form of cryptococcal meningitis.
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