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Updated: May 4, 2026

Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
[Toilet of chronic wound]
Nevenka Strok1, Dubravko Huljev2
1Klinicka bolnica Sveti Duh, Klinika za kirurgiju, Zagreb, Hrvatska. nstrok@kbsd.hr
Abstract:
Chronic wound toilet, with appropriate care of the surrounding skin, is one of the basic steps that must be performed in the treatment of patients with chronic wound. On wound cleaning and bandaging, it is of utmost importance to choose an appropriate technique of cleansing, select an appropriate solution for leaching and choose an appropriate wound dressing. In this way, the wound is protected from dirt from the environment and microorganisms, while protecting the surrounding tissue from the wound exudate, providing optimal conditions for better and faster wound healing and contributing to improved patient quality of life. The frequency of dressing change is individual and must be tailored to each patient in correlation with the psychosocial status of the patient, the type of the wound, the amount and type of wound exudate, as well as what is to be put on the wound. One of the most important elements in wound toilet is appropriate care for the surrounding skin. Basic guidelines for skin care must meet three basic criteria: adequate washing and cleansing of the skin, maintain the physiological balance of the skin and protect the skin from external damage.
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