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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Same author

[Obstacles in wound healing].

Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti·2013
Same author

[Prevention of pressure ulcer (bedsore)].

Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti·2013
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[Toilet of chronic wound].

Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti·2013
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[Debridement- crucial procedure in the treatment of chronic wounds].

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[Setting of compression therapy].

Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti·2013
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[Modern wound dressings].

Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti·2013

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Updated: May 4, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
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[Negative pressure therapy- supportive method in chronic wound treatment].

Dubravko Huljev1

  • 1Klinicka bolnica Sveti Duh, Klinika za kirurgiju, Centarza plasticnu i rekonstruktivnu krurgiju, Zagreb, Hrvatska. dhuljev@kbsd.hr

Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti
|December 31, 2013
PubMed
Summary

Negative pressure sound therapy (NPST) accelerates chronic wound healing. This supportive treatment enhances blood flow, reduces bacteria, and promotes tissue repair, outperforming other conservative methods.

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Area of Science:

  • Wound healing research
  • Biomedical engineering
  • Regenerative medicine

Background:

  • Chronic wounds pose significant treatment challenges.
  • Current conservative treatments often have limited efficacy.
  • Negative pressure wound therapy (NPWT) is an established supportive option.

Purpose of the Study:

  • To evaluate the efficacy of negative pressure sound therapy (NPST) as a supportive treatment for chronic wounds.
  • To investigate the impact of NPST on key wound healing parameters.
  • To compare NPST outcomes with traditional conservative wound care.

Main Methods:

  • Utilized negative pressure sound therapy as an intervention.
  • Monitored wound healing indicators including angiogenesis, blood flow, edema, and tissue granulation.
  • Assessed bacterial burden and levels of harmful wound byproducts.
  • Compared healing times with conventional treatments.

Main Results:

  • NPST demonstrated positive effects on angiogenesis and wound blood flow.
  • Significant reduction in edema and improved wound moisture balance observed.
  • Stimulation of granulation tissue and wound retraction were noted.
  • Marked decrease in bacterial load and harmful substances like endotoxins.
  • Accelerated healing time compared to other conservative therapies.

Conclusions:

  • Negative pressure sound therapy is a promising supportive treatment for chronic wounds.
  • NPST effectively promotes wound healing through multiple mechanisms.
  • NPST offers a potentially faster and more effective alternative to conventional wound care.