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OPTN/SRTR 2012 Annual Data Report: lung.

M Valapour1, M A Skeans, B M Heubner

  • 1Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Minnesota, Minneapolis, MN.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|December 31, 2013
PubMed
Summary
This summary is machine-generated.

Lung transplant wait times averaged 4 months in 2012, with survival rates improving. Lung transplant recipients experienced higher rehospitalization rates compared to other organ transplant recipients.

Keywords:
End-stage lung diseasesLung Allocation Scorelung transplantorgan allocationtransplant outcomes

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Area of Science:

  • Medicine
  • Surgery
  • Pulmonology

Background:

  • Lung transplantation is a critical treatment for end-stage lung diseases.
  • Organ allocation considers age, geography, blood type, and the Lung Allocation Score.
  • The Lung Allocation Score assesses wait-list mortality risk and post-transplant survival probability.

Purpose of the Study:

  • To analyze lung transplant wait times and survival statistics.
  • To compare lung transplant outcomes with other solid organ transplants.
  • To examine rehospitalization rates for lung transplant recipients.

Main Methods:

  • Analysis of lung transplant candidate data from 2012.
  • Evaluation of wait times based on donation service area.
  • Assessment of patient and graft survival rates.
  • Comparison of rehospitalization rates with other solid organ transplant recipients.

Main Results:

  • Median wait time for lung transplants was 4 months in 2012.
  • 65.3% of candidates received a transplant within one year, with significant regional variation.
  • Median survival was 5.3 years, and conditional survival after one year was 6.7 years.
  • Pediatric candidates faced varied wait times, with over a third waiting 4+ years.
  • Lung transplant recipients had higher rehospitalization rates (43.7/100 in year 1, 36.0/100 in year 2) than other solid organ transplant recipients.

Conclusions:

  • Lung transplant outcomes, including survival, show continuous improvement.
  • Survival rates are better for recipients aged 6-11 years compared to younger children.
  • Lung transplant recipients face a higher burden of post-transplant complications requiring rehospitalization.