Related Experiment Video
Updated: Sep 10, 2026
10:22
Enrichment of Bruch's Membrane from Human Donor Eyes
Published on: November 15, 2015
[Hereditary drusen in Bruch's membrane]
Klinische Monatsblatter Fur Augenheilkunde
|January 1, 1987
Abstract:
The left eye of a 71-year-old patient who had suffered from choroiditis guttata was removed immediately after death by enucleation. Histopathological studies revealed numerous nodular (hard) drusen, a wide variety of senile alterations of the pigment epithelium and Bruch's membrane, and the presence of multiple corpora arenacea in the subarachnoid space of the optic nerve. A new hypothesis concerning the development of hereditary drusen is advanced, postulating a disturbance of the lysosomal enzyme/inhibitor balance.
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