Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 4, 2026

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol
07:59

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol

Published on: July 28, 2018

10.9K

First closed-loop goal directed fluid therapy during surgery: a pilot study.

J Rinehart1, Y Le Manach2, H Douiri3

  • 1Department of anesthesiology and perioperative care, university of California Irvine, 101 S City Drive, Orange, CA 92868 Irvine, CA, USA.

Annales Francaises D'Anesthesie Et De Reanimation
|January 1, 2014
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erythrocyte antigens and antibodies in the Chilean population.

Immunohematology·2021
Same author

Ultrafast carbon nanotubes growth on recycled carbon fibers and their evaluation on interfacial shear strength in reinforced composites.

Scientific reports·2021
Same author

Goal-Directed fluid therapy with closed-loop assistance during moderate risk surgery using noninvasive cardiac output monitoring: A pilot study.

British journal of anaesthesia·2015
Same author

Biodesulfurization of dibenzothiophene and gas oil using a bioreactor containing a catalytic bed with Rhodococcus rhodochrous immobilized on silica.

Biotechnology letters·2014
Same author

Cognitive errors detected in anaesthesiology: a literature review and pilot study.

British journal of anaesthesia·2011
Same author

Conservation. High value and long life--double jeopardy for tunas and billfishes.

Science (New York, N.Y.)·2011
Same journal

Annales francaises d'anesthesie et de reanimation·2020
Same journal

[Multimodal approach to enhance filter lifespan: are all actions equal?].

Annales francaises d'anesthesie et de reanimation·2014
Same journal

[Disparity of French Emergency medical services equipment: disparity of funding allocation or of management quality?].

Annales francaises d'anesthesie et de reanimation·2014
Same journal

[Eligibility to a Maastricht III - type organ donation according to the protocol proposed by the French organ procurement organization (Agence de la biomedicine) among patients in a medico surgical intensive care unit].

Annales francaises d'anesthesie et de reanimation·2014
Same journal

[Enhanced recovery after elective colorectal surgery: reply].

Annales francaises d'anesthesie et de reanimation·2014
Same journal

[Aorto-right atrial fistula as complication of aortic dissection].

Annales francaises d'anesthesie et de reanimation·2014
See all related articles
This summary is machine-generated.

A novel closed-loop system for Goal Directed Fluid Therapy (GDFT) was successfully used in 12 patients undergoing major surgery. This automated approach ensured high compliance with fluid management protocols, improving patient outcomes.

Area of Science:

  • Anesthesiology
  • Critical Care Medicine
  • Medical Engineering

Background:

  • Goal Directed Fluid Therapy (GDFT) optimizes intraoperative fluid management to improve patient outcomes.
  • Current GDFT protocols require continuous monitoring and adjustments by anesthesiologists.
  • Automating GDFT could enhance consistency and efficiency in fluid administration.

Purpose of the Study:

  • To describe the first clinical use of a closed-loop fluid management system.
  • To automatically apply Goal Directed Fluid Therapy (GDFT) protocols.
  • To assess the system's ability to maintain hemodynamic optimization during major surgery.

Main Methods:

  • Prospective pilot study involving 12 patients undergoing major surgery.
  • A closed-loop controller system monitored stroke volume variation and stroke volume.
Keywords:
Chirurgie majeureClosed-loopFluidFluid responsivenessGoal directed therapyHaemodynamicHémodynamiqueRemplissageRéponse au remplissageSafety

More Related Videos

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver
12:27

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver

Published on: June 16, 2023

4.4K

Related Experiment Videos

Last Updated: May 4, 2026

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol
07:59

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol

Published on: July 28, 2018

10.9K
Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver
12:27

Modified Laparoscopic Anatomic Hepatectomy: Two-Surgeon Technique Combined with the Simple Extracorporeal Pringle Maneuver

Published on: June 16, 2023

4.4K
  • Compliance defined as >85% of surgery time in a preload-independent state (SVI <13%) or average cardiac index >= 2.5 L/min/m².

    • Main Results:

    • The closed-loop GDFT system was successfully implemented in all 12 patients.
    • Patients spent a median of 91% of surgery time in a preload-independent state.
    • All 12 patients met the predefined criteria for compliance with intraoperative GDFT management.

    Conclusions:

    • Closed-loop GDFT delivery under anesthesiologist guidance achieved targeted hemodynamic objectives for 91% of surgery time.
    • This automated system shows potential for consistent, high-quality fluid administration.
    • The approach may enhance compliance with perioperative goal-directed therapy.