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Published on: October 6, 2022
Decreasing cardiovascular risk in HIV infection between 2005 and 2011
Giuseppe V De Socio1, Giustino Parruti, Elena Ricci
1aDepartment of Infectious Diseases, Azienda Ospedaliero-Universitaria di Perugia, Perugia bDepartment of Infectious Diseases, Pescara Hospital, Pescara cDepartment of Infectious Diseases, Luigi Sacco Hospital, Milan dDepartment of Infectious Diseases, University of Bari, Bari eDepartment of Infectious Diseases, Garibaldi Hospital, University of Catania, Catania fDepartment of Infectious Diseases, Galliera Hospital, Genoa, Genoa gDepartment of Infectious Diseases, Careggi Hospital, Florence hDepartment of Infectious Diseases, University of Milan, Milan iDepartment of Infectious Diseases, San Martino Hospital Genoa, University of Genoa, Genoa jDepartment of Infectious Diseases, Manzoni Hospital, Lecco kUniversità di Perugia and Struttura Complessa di Medicina Interna, Azienda Ospedaliero-Universitaria di Terni, Terni, Italy.
Abstract:
Cardiovascular risk profile was compared in 765 Italian HIV-infected outpatients enrolled in 2005 and in 765 individually age-matched and sex-matched patients enrolled in 2011. Median Framingham risk score was 8.6% in 2005 vs. 7.9% in 2011 (P = 0.04); metabolic syndrome was present in 40.3% vs. 33.4% (P = 0.006). Blood glucose, triglycerides, prevalence of smokers, and lipodystrophy were all significantly lower in 2011 (all P < 0.0001). Cardiovascular risk improved over a 6-year period in Italian HIV-infected patients.
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