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Large ameloblastic carcinoma: A rare case with management.

Dominic Augustine1, B Sekar2, S Murali2

  • 1Department of Oral Pathology, Bangalore Institute of Dental Sciences and Hospital, Bangalore, Karnataka, India.

Dental Research Journal
|January 1, 2014
PubMed
Summary

Ameloblastic carcinoma, a rare malignant tumor, requires aggressive treatment. This case highlights unique features and extensive mandibular involvement in a female patient.

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Area of Science:

  • Oral and Maxillofacial Pathology
  • Surgical Oncology
  • Odontogenic Tumors

Background:

  • Ameloblastic carcinoma is the malignant counterpart of ameloblastoma, necessitating a more aggressive surgical approach.
  • Limited documented cases hinder understanding of ameloblastic carcinoma's biologic activity and behavior.
  • Accurate diagnosis and treatment planning are crucial for managing this rare malignancy.

Observation:

  • A rare case of ameloblastic carcinoma in a 44-year-old female is presented.
  • The tumor presented as a large lesion involving the entire mandible, from the left ramus to the right ramus.
  • Unique histopathologic features and aggressive clinical behavior were observed.

Findings:

  • The ameloblastic carcinoma exhibited distinct histopathologic characteristics.
Keywords:
Ameloblastic carcinomamalignant counterpartmandible

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  • The extensive mandibular involvement (left ramus to right ramus) is an unusual presentation.
  • The lesion demonstrated aggressive behavior, requiring radical surgical intervention.
  • Implications:

    • This case underscores the importance of recognizing the aggressive nature of ameloblastic carcinoma.
    • Radical surgery and reconstruction are vital for managing extensive mandibular ameloblastic carcinoma.
    • Further documentation of rare cases is needed to elucidate the biologic activity of ameloblastic carcinoma.