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Updated: May 4, 2026

Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
[Periapical regeneration. About one case of necrotic immature tooth treated with mineral trioxide aggregate (MTA)]
1Sce odontologie conservatrice-endodontie, Faculté de médecine dentaire de Casablanca, Maroc.
Abstract:
Therapeutic of apexification with calcium hydroxide has been extensively used in clinical practice, but this technique has some drawbacks (long duration of treatment, weakening of the radicular walls). Different studies have proposed to close the apex opened with MTA (Mineral trioxide Aggregate) which is biocompatible, bacteriostatic, this material induces regeneration of the periapical region through the formation of cementum, bone and periodontal ligament (1, 2). This case report describes the technique of setting up in a single step of the Mineral trioxide Aggregate as an apical barrier for immature permanent roots. This method has allowed us an immediate apical sealing and a root canal filling and a coronary restore permanently as soon as possible. The radiological control confirmed that this type of apexification could be successful with periapical regeneration ad-integrum.

