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Updated: May 4, 2026

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
[Study on the secondary metabolites from marine sponge Phakellia fusca]
Zhou Deng1, Li-Dan Tang2, Xiao-Jian Liao2
1Department of Chemistry, Jinan University, Guangzhou 510632, China. dz_203@hotmail.com
Objective:
To study the secondary metabolites from marine sponge Phakellia fusca.
Methods:
The compounds were isolated by column chromatography over silica gel and purified by Sephadex LH-20 column chromategraphy and preparative TLC. The structures were elucidated by means of physiochemical properties and spectroscopic analysis.
Results:
Ten compounds were separated and identified as: p-hydroxybenzoic acid (1), cetanic acid (2), batyl alcohol (3), cety ethers of glycerol (4), (E)-N-2-(1,3-dihydroxy octadecan-4-en)-hexade-camide (5), thymidine (6), cyclo-(L-Tyr-L-Pro) (7), phenyl acetylamine (8), uracil (9),4-hydroxybenzamide (10).
Conclusion:
Compound 5, 7 and 10 are isolated from Phakellia fusca for the first time.

