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External validation of a model for periconceptional prediction of recurrent early-onset preeclampsia
S M van Kuijk1, D H Delahaije, C D Dirksen
1Department of Obstetrics and Gynaecology, Maastricht University Medical Centre , Maastricht , the Netherlands .
Objective:
To validate a previously published prediction model for recurrent early-onset preeclampsia (PE).
Methods:
We included 229 pregnant women with a history of early-onset PE and computed their risk using the prediction model, compared the predicted risk to their pregnancy outcomes and assessed performance of the model.
Results:
Early-onset PE recurred in 6.6% of participants. The area under the receiver operating characteristic curve was 59% (95% CI: 45-73). The model created groups that were only moderately different in terms of their risk.
Conclusions:
The model's discriminate ability was poor and predictive performance insufficient to classify women into relevant risk groups.
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