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Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
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[Biologic therapy in idiopathic inflammatory myopathy]

Albert Selva-O'Callaghan1, Manel Ramos Casals2, Josep M Grau Junyent3

  • 1Servicio de Medicina Interna, Hospital General Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, España.

Medicina Clinica
|January 8, 2014
PubMed

The aim of this article is to study the evidence-based knowledge related to the use of biological therapies in patients diagnosed with idiopathic inflammatory myopathy (dermatomyositis, polymyositis and inclusion body myositis). In this review the leading published studies related to the use of biological therapy in patients with myositis are analysed; mainly those with high methodological standards, that means randomized and controlled studies. Methodological drawbacks due to the rarity and heterogeneity of these complex diseases are also addressed. Up to now is not possible to ascertain the biologics as a recommended therapy in patients with myositis, at least based in the current evidence-based knowledge, although it can not be neglected as a therapeutic option in some clinical situations, taking into account the scarce of effective treatments in those patients, especially in refractory myositis. Future studies probably will help to better define the role of biological therapies in patients with idiopathic inflammatory myopathy.

Keywords:
Biologic therapyIdiopathic inflammatory myopathyMiopatía inflamatoria idiopáticaMiositisMyositisTerapia biológica

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