Surface treatments of silver rods with enhanced iodide adsorption for I-125 brachytherapy seeds
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Updated: May 4, 2026

An Efficient Method for Selective Desalination of Radioactive Iodine Anions by Using Gold Nanoparticles-Embedded Membrane Filter
Published on: July 13, 2018
Jin Hee Lee1, Kang Hyuk Choi2, Kook Hyun Yu3
1Instrumental Analysis Laboratory, Department of Chemistry, Dongguk University, Seoul 100-715, Republic of Korea; Korea Atomic Energy Research Institute, P.O. Box 105, Yuseong, Daejeon 305-600, Republic of Korea.
Abstract:
This study described an effective method to load (125)I on silver rods for the preparation of a brachytherapy source. We tested various ligands on the silver rod surface to screen the one with the highest adsorption and specific radioactivity. In addition, we investigated the effect of surface etching to increase the adsorption capability followed by the extended surface area. We also found that the use of an oxidant during iodide adsorption can increase the loading significantly. The maximum activity of 137.90MBq/rod (3.7269mCi/rod) was achieved on the etched silver rods with phosphate ligand and hydrogen peroxide as an oxidant. In addition, this is 4.5-fold higher than that of the conventional chloride treatment method.
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