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Updated: May 4, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
[Mid-gastrointestinal bleeding - endoscopy sheds light in the darkness]
1Klinik für Innere Medizin II: Gastroenterologie, Hepatologie, Endokrinologie, Pneumologie, HSK Wiesbaden, Deutschland.
Mid-gastrointestinal bleeding (MGI) diagnosis relies on small bowel endoscopy. Flexible enteroscopy, particularly balloon-assisted enteroscopy (DBE), is now preferred over older methods for its diagnostic and therapeutic capabilities.
Area of Science:
- Gastroenterology
- Endoscopy
- Diagnostic Imaging
Context:
- Mid-gastrointestinal bleeding (MGI) is a common indication for small bowel endoscopy.
- Intraoperative enteroscopy was the gold standard but is now a reserve method.
- Several non-surgical, flexible enteroscopy techniques are available, with balloon-assisted enteroscopy (BAE) prevalent in Europe.
Purpose:
- To review the current landscape of small bowel endoscopy techniques for diagnosing and treating MGI.
- To compare the efficacy and applications of capsule endoscopy, balloon-assisted enteroscopy (DBE, SBE), and angiography.
Summary:
- Capsule endoscopy is ideal for chronic MGI or screening.
- Flexible enteroscopy techniques, especially double balloon enteroscopy (DBE), offer high diagnostic yield and therapeutic intervention for acute MGI.
- DBE is the most studied flexible enteroscopy technique, providing the highest complete enteroscopy rate.
- Angiography (CT and conventional) with embolization is valuable for difficult cases with unsuccessful enteroscopy.
Impact:
- Flexible enteroscopy, particularly DBE, has become the primary tool for MGI diagnosis and treatment.
- Advances in enteroscopy aim to improve ease and speed of procedures.
- Angiography remains a crucial option for refractory cases, highlighting a multimodal approach to MGI management.
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