Related Experiment Video
Updated: May 4, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
Transcatheter pulmonary valve insertion, expanded use and future directions.
Jeremy M Ringewald1, Elsa J Suh1
1Division of Pediatric Cardiology, The Congenital Heart Institute of Florida (CHIF), St. Joseph's Children's Hospital of Tampa, Pediatric Cardiology Associates/Pediatrix Medical Group, Saint Petersburg, Florida, United States of America.
Transcatheter pulmonary valve replacement using the Melody® valve offers a less invasive option for congenital heart disease patients. This approach can extend time between surgeries and potentially reduce long-term complications.
Area of Science:
- Cardiology
- Medical Devices
- Congenital Heart Disease Management
Background:
- Surgical pulmonary valve replacement is a common procedure for patients with congenital heart disease.
- Repeated sternotomies carry significant morbidity.
- Transcatheter pulmonary valve replacement (TPVR) offers a less invasive alternative.
Observation:
- The Melody® valve is an established technology for TPVR.
- Expanded applications for TPVR are emerging.
- Combined surgical and percutaneous approaches are being utilized.
Findings:
- TPVR with the Melody® valve is a viable alternative to surgical replacement for select patients.
- This technology can prolong the interval between sternotomies.
- It has the potential to reduce late morbidity.
Implications:
- TPVR represents a complementary strategy in the long-term management of congenital heart disease.
- This approach may improve late outcomes and diminish morbidity.
- Future directions in evolving TPVR technology are promising.
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Mitral Stenosis III: Medical Management
Cardiac Catheterization II: Right Heart Catheterization

