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Updated: May 4, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Anesthesia management for MitraClip device implantation.
Harikrishnan Kothandan1, Kian Ho Vui, Vui Kian Ho
1Department of Cardiothoracic Anaesthesia, National Heart Centre, Singapore.
Percutaneous MitraClip implantation offers a viable treatment for severe mitral regurgitation in high-risk patients. This minimally invasive procedure effectively reduces mitral regurgitation, improving patient outcomes.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Devices
Background:
- Severe mitral regurgitation (MR) poses significant risks for patients unsuitable for traditional surgery.
- Percutaneous MitraClip implantation provides an alternative therapeutic option.
Purpose of the Study:
- To evaluate the feasibility and outcomes of percutaneous MitraClip implantation in high-risk patients with symptomatic severe MR.
- To assess the role of anesthesia and imaging guidance in the procedure.
Main Methods:
- Retrospective analysis of peri-operative data from 21 patients undergoing MitraClip implantation.
- Procedures guided by 3D transesophageal echocardiography (TEE) and fluoroscopy under general anesthesia.
- Monitoring of activated clotting time and post-procedure ICU care.
Main Results:
- MitraClip implantation was successful in 19 out of 21 patients, with 2 cases aborted due to complications.
- Significant reduction in severe MR to mild-moderate MR was observed in implanted patients.
- Procedure performed in catheterization lab or hybrid operating theatre.
Conclusions:
- Percutaneous MitraClip implantation is a feasible alternative for high-risk patients with severe MR.
- Anesthesia management is comparable to open mitral valve surgery.
- Transesophageal echocardiography (TEE) is crucial for successful MitraClip procedures.
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