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Management of chronic pain.

F J Meyers, F H Meyers

American Family Physician

|July 1, 1987

Summary

Effective pain management for cancer patients is possible without drug toxicity by selecting potent medications and appropriate administration routes. Combining drug classes and utilizing special administration methods can manage tolerance, benefiting other severe pain conditions too.

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Area of Science:

Oncology
Pharmacology
Pain Management

Background:

Cancer pain management often involves complex challenges.
Achieving pain relief without adverse drug effects is a primary goal.

Purpose of the Study:

To outline pharmacologic principles for effective cancer pain relief.
To address challenges like drug tolerance in pain management.

Main Methods:

Selection of pharmacologic agents based on potency.
Consideration of various routes of drug administration.
Combination therapy using different drug classes (e.g., phenothiazines, aspirin).

Main Results:

Adherence to pharmacologic principles can lead to pain relief without toxicity.
Tolerance can be effectively managed through combined therapies and specialized administration routes.
Similar palliative approaches are effective for severe non-cancer pain.

Conclusions:

Basic pharmacologic principles are key to safe and effective cancer pain management.
Tolerance management strategies enhance treatment efficacy.
The outlined principles offer a framework for managing severe pain in various patient populations.

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