Intraductal radiofrequency ablation for refractory benign biliary stricture: pilot feasibility study
Bing Hu1, Dao-Jian Gao, Jun Wu
1Department of Endoscopy, Eastern Hepatobiliary Hospital, The Second Military Medical University, Shanghai, China.
Radiofrequency ablation (RFA) offers a new endoscopic approach for benign biliary stricture (BBS). This initial study shows RFA is safe and effective for BBS management, particularly in difficult cases.
Area of Science:
- Gastroenterology
- Interventional Endoscopy
- Biliary Interventions
Background:
- Benign biliary stricture (BBS) management is challenging.
- Endoscopic treatment options for biliary fibroplasia are limited.
- Radiofrequency ablation (RFA) is explored for BBS.
Purpose of the Study:
- To evaluate the initial safety and efficacy of endobiliary RFA for benign biliary stricture (BBS).
Main Methods:
- Nine patients with BBS underwent intraductal bipolar RFA (10 W, 90 s) followed by balloon dilatation.
- Patients had various causes of BBS including post-operation, liver transplant, and chronic inflammation.
- Seven patients had prior failed interventions.
Main Results:
- Immediate stricture improvement was observed in all patients post-RFA.
- One patient experienced mild pancreatitis; no severe adverse events occurred.
- BBS resolution without further stenting was achieved in four patients at a median 12.6-month follow-up.
Conclusions:
- Endobiliary RFA shows promise as a safe and effective treatment for benign biliary stricture (BBS).
- RFA is particularly beneficial for refractory BBS cases.
- Further research is needed to confirm these findings.
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