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Updated: May 4, 2026

$Crystallization of Proteins on Chip by Microdialysis for In Situ X-ray Diffraction Studies$

Crystallization of Proteins on Chip by Microdialysis for In Situ X-ray Diffraction Studies

Published on: April 11, 2021

Tip induced crystallization lithography.

Xin Zhang¹, Brandon L Weeks

¹Department of Chemical Engineering, Texas Tech University , Lubbock Texas 79409, United States.

Journal of the American Chemical Society

|January 11, 2014

Summary

This summary is machine-generated.

We developed a new method called tip induced crystallization lithography (TICL) to create large organic crystal arrays. This technique uses an atomic force microscope tip to precisely crystallize organic thin films, enabling the fabrication of features smaller than 1 micrometer.

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Patterning via Optical Saturable Transitions - Fabrication and Characterization

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$Crystallization of Proteins on Chip by Microdialysis for In Situ X-ray Diffraction Studies$

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Patterning via Optical Saturable Transitions - Fabrication and Characterization

Patterning via Optical Saturable Transitions - Fabrication and Characterization

Published on: December 11, 2014

Area of Science:

Materials Science
Nanotechnology
Organic Electronics

Background:

Fabricating ordered organic crystal arrays is crucial for advanced electronic devices.
Existing methods for creating organic crystal patterns often face limitations in scalability and feature size.

Purpose of the Study:

To introduce and demonstrate a novel, efficient technique for fabricating large-area organic crystal arrays.
To showcase the capability of the new method in producing sub-micrometer features.

Main Methods:

Utilizing tip induced crystallization lithography (TICL) on amorphous organic thin films.
Employing an atomic force microscope tip to induce localized crystallization.
Removing non-crystalline material via heating or washing to leave stable crystal arrays.

Main Results:

Successfully fabricated large-area organic crystal arrays on various substrates.
Demonstrated the ability to create features with sizes less than 1 micrometer using TICL.
Achieved stable organic crystal arrays after removal of amorphous regions.

Conclusions:

Tip induced crystallization lithography (TICL) offers an efficient and scalable approach for fabricating complex organic crystal patterns.
The technique holds promise for the development of next-generation organic electronic devices requiring precise nanoscale patterning.