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Updated: Feb 14, 2026

Preparation of Giant Vesicles Encapsulating Microspheres by Centrifugation of a Water-in-oil Emulsion
Published on: January 24, 2017
Preparation of size tunable giant vesicles from cross-linked dextran(ethylene glycol) hydrogels
Néstor López Mora1, Jesper S Hansen, Yue Gao
1Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands. a.kros@chem.leidenuniv.nl.
Abstract:
We present a novel chemically cross-linked dextran-poly(ethylene glycol) hydrogel substrate for the preparation of dense vesicle suspensions under physiological ionic strength conditions. These vesicles can be easily diluted for individual study. Modulating the degree of cross-linking within the hydrogel network results in tuning of the vesicle size distribution.
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