Related Experiment Video
Updated: May 4, 2026

Orienteering as a Tool for Cognitive Research: An Implementation Guide
Published on: November 29, 2024
The Impact of Exercise, Cognitive Activities, and Socialization on Cognitive Function: Results From the National
M Kathryn Jedrziewski1, Douglas C Ewbank2, Haidong Wang3
1The Institute on Aging, University of Pennsylvania, Philadelphia, PA, USA Marian S. Ware Alzheimer Program, University of Pennsylvania, Philadelphia, PA, USA Alzheimer's Disease Core Center, University of Pennsylvania, Philadelphia, PA, USA Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA jedrzmk@mail.med.upenn.edu.
Abstract:
Currently, there are no effective treatments for Alzheimer's disease and related disorders and age continues to be a robust risk factor. Thus, population aging in the United States may have catastrophic results if interventions are not found and implemented. This study examines possible associations between cognitive impairment and exercise, cognitive activities, and socialization. Cognitive activities, socialization, and exercise were assessed at baseline, and cognitive function was measured at baseline, 5-year, and 10-year follow-up. Controlling for baseline cognitive function, age, sex, education, diabetes, and hypertension, linear regression was performed. Engagement in cognitive activities was inversely associated with the onset of cognitive impairment at 5-year follow-up but was no longer significant at 10-year follow-up. Exercise was associated with a lower risk of cognitive impairment at 10-year follow-up but was not significant at 5-year follow-up. Associations with socialization were not statistically significant at either follow-up.
More Related Videos
07:01Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
Published on: September 20, 2020
10:19Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
Published on: August 22, 2014
Related Concept Videos
Cognitive Development During Adulthood
Longitudinal Research
Longitudinal Studies
Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
The Effect of Aging on Tissues