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Updated: May 4, 2026

Surgical Procedures and Methodology for a Preclinical Murine Model of De Novo Mammary Cancer Metastasis
Published on: July 29, 2017
[History and care of malignant wounds in breast cancer]
Isabelle Fromantin1, Séverine Alran2, Nathalie Cassoux2
1Département des soins de support, unité de soins des plaies, Institut Curie, 26, rue d'Ulm 75248 Paris cedex 05, France. isabelle.fromantin@curie.net
Abstract:
The first descriptions of ulcerated breast cancer date back to ancient Egypt. From the Greek and Roman periods to the Renaissance, fungating wounds were described, excised, cauterized and necrotized using various techniques and unguents. The foundations of some of the therapeutic strategies we still use today were developed.Today the management of inoperable malignant wounds that are not amenable to anti-cancer treatment remains complex and the symptoms are difficult to control.
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