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Fecal micro RNA Isolation
Published on: October 28, 2020
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[MicroRNA regulation on host-microbiota interaction--a review]
1Laboratory of Gastrointestinal Microbiology, Nanjing Agricultural University, Nanjing 210095, China. muchunlong@hotmail.com
Wei Sheng Wu Xue Bao = Acta Microbiologica Sinica
|January 14, 2014
Summary
The gut microbiota influences intestinal health and immunity through complex interactions. MicroRNAs play a key role in mediating these host-microbiota communications, impacting gut homeostasis.
Area of Science:
- Microbiology
- Immunology
- Molecular Biology
Context:
- The intestinal environment relies on intricate host-microbiota interactions.
- Gut microbiota antigens and metabolites significantly influence intestinal immunological homeostasis and nutrient assimilation.
- MicroRNAs are crucial intracellular regulators of host gene expression.
Purpose:
- To summarize recent advancements in understanding host-microbiota interactions.
- To highlight the role of microRNA in regulating gut homeostasis.
- To explore microRNA's influence on host-microbiota communication.
Summary:
- Gut microbiota impacts host immunity and metabolism, with microbial metabolites regulating bacterial communities and nutrient absorption.
- MicroRNAs mediate host gene expression, influencing mRNA transcription and post-transcriptional modification.
- Emerging research shows gut microbiota alters microRNA expression involved in gut inflammation and mucosal barrier function.
Impact:
- Provides a comprehensive overview of microRNA's regulatory role in the gut.
- Enhances understanding of host-microbiota interactions in maintaining intestinal health.
- Identifies microRNAs as critical mediators in gut inflammation and mucosal barrier regulation.
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