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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

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Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
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Mitral Stenosis I: Introduction01:22

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Mitral Valve Prolapse I: Introduction01:27

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IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
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Mitral Valve Prolapse II: Assessment and Management01:22

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IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
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Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

557
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
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Updated: May 4, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
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Mitral annuloplasty using an intra-annular ring.

Mustafa Cikirikcioglu1, Sanjay Cherian, Afksendiyos Kalangos

  • 1Division of Cardiovascular Surgery, University Hospitals and Medical Faculty of Geneva, Switzerland.

Multimedia Manual of Cardiothoracic Surgery : MMCTS
|January 14, 2014
PubMed
Summary
This summary is machine-generated.

A novel biodegradable annuloplasty ring implanted within the mitral annulus reduces thromboembolic risks and supports pediatric growth. This technique offers a safer alternative to conventional rings, eliminating the need for anticoagulation.

Keywords:
AnnuloplastyBiodegradableMitral annulusMitral repairMitral valve

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Area of Science:

  • Cardiovascular Surgery
  • Biomaterials Science
  • Pediatric Cardiology

Background:

  • Mitral valve repair often involves annuloplasty rings to remodel the annulus and enhance repair durability.
  • Conventional annuloplasty rings are permanent foreign bodies, increasing thromboembolic complication risks and are not optimized for pediatric patients.

Purpose of the Study:

  • To introduce a novel intra-annular, biodegradable annuloplasty ring for mitral valve repair in adults and children.
  • To present the implantation technique and rationale for this new biodegradable ring.

Main Methods:

  • Development of an intra-annular ring designed for gradual hydrolysis and degradation.
  • Implantation of the ring 'into' the annulus, rather than 'onto' it, to minimize blood contact.

Main Results:

  • The biodegradable ring induces fibrosis and remodels the posterior mitral annulus.
  • Intra-annular implantation prevents direct contact with circulating blood, reducing thromboembolic risks and negating anticoagulation needs.
  • The ring allows for normal valve orifice growth in pediatric patients.

Conclusions:

  • The intra-annular biodegradable annuloplasty ring represents a significant advancement in mitral valve repair, offering improved safety and pediatric suitability.
  • This innovative approach minimizes complications associated with permanent foreign bodies and addresses the specific needs of the pediatric population.