Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Preeclampsia, delivery, and the hemostatic system.

A A Saleh, S F Bottoms, R A Welch

    American Journal of Obstetrics and Gynecology
    |August 1, 1987
    PubMed
    Summary

    Preeclampsia is linked to hemostatic system changes, including endothelial injury and altered clotting and fibrinolysis. These markers improve after delivery, suggesting rapid resolution of endothelial injury in preeclamptic patients.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A cancelable ear recognition system via optimized deep feature fusion.

    Scientific reports·2026
    Same author

    Cervical lymph node TB: diagnostic yield and patient profile.

    IJTLD open·2026
    Same author

    Enhancement of the structure and linear/nonlinear optical properties of PVA/chitosan/Ag nanocomposites for optoelectronic and antibacterial applications.

    Scientific reports·2025
    Same author

    Optimal planning of integrated nuclear-hybrid renewable energy systems for electrical distribution networks based on artificial intelligence.

    Scientific reports·2025
    Same author

    Ultrasound as a triaging tool for the diagnosis of malaria and typhoid in a resource constrained setting: A proposed frame-work.

    Radiography (London, England : 1995)·2024
    Same author

    Computer vision syndrome and dry eye symptoms among breastfeeding women.

    The Medical journal of Malaysia·2024

    Area of Science:

    • Obstetrics and Gynecology
    • Hematology
    • Perinatology

    Background:

    • Preeclampsia is a pregnancy complication characterized by high blood pressure and potential organ damage.
    • The hemostatic system plays a crucial role in pregnancy, and its dysregulation is implicated in preeclampsia.
    • Understanding the hemostatic changes associated with preeclampsia and delivery is vital for patient management.

    Purpose of the Study:

    • To investigate the impact of preeclampsia and delivery on key components of the hemostatic system.
    • To assess markers of endothelial injury, coagulation, and fibrinolysis in preeclamptic versus control pregnancies.
    • To evaluate the resolution of these hemostatic changes postpartum.

    Main Methods:

    • Prospective study of 59 nulliparous patients.

    Related Experiment Videos

  • Hemostatic system evaluation (fibronectin, antithrombin III, alpha 2-antiplasmin) before and 24-48 hours after delivery.
  • Comparison between mild preeclampsia, severe preeclampsia, and pregnant control groups.

    • Main Results:

    • Preeclampsia associated with elevated fibronectin, reduced antithrombin III, and decreased alpha 2-antiplasmin.
    • Post-delivery, fibronectin decreased significantly only in preeclamptic patients.
    • Alpha 2-antiplasmin levels increased in all groups after delivery.

    Conclusions:

    • Preeclampsia involves endothelial injury, hypercoagulability, and altered fibrinolysis.
    • These hemostatic abnormalities appear to resolve rapidly postpartum.
    • Resolution of endothelial injury post-delivery likely contributes to clinical improvement in the early puerperium.