Related Experiment Video
Updated: May 4, 2026

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
Published on: April 4, 2022
Angina pectoris: current therapy and future treatment options.
Raj Parikh1, Philip J Kadowitz
1Rush University Medical Center, 1700 W Van Buren St, Chicago, IL 60612, USA.
Angina pectoris, characterized by chest pain due to heart blood supply issues, affects half a million people annually. This review covers current and novel treatments, including medical, surgical, and stem cell therapies for angina management.
Area of Science:
- Cardiology
- Cardiovascular Medicine
Background:
- Angina pectoris is a common clinical complaint resulting from myocardial ischemia, where heart blood supply cannot meet demand.
- It manifests as chest pain or discomfort and is a significant cause of morbidity, with approximately 500,000 new cases annually.
- Cardiac-related chest pain is considered the most lethal etiology of chest pain.
Purpose of the Study:
- To review current medical and surgical therapies for angina management.
- To summarize key clinical trials that have informed angina treatment strategies.
- To explore emerging and novel therapeutic options for angina.
Main Methods:
- Literature review of existing medical and surgical treatments for angina.
- Analysis of clinical trial data supporting current therapeutic approaches.
- Focused review of innovative and investigational therapies, including stem cell applications.
Main Results:
- Current management of angina involves established medical and surgical interventions.
- Clinical trials have been instrumental in validating and refining these therapies.
- Novel treatment avenues, such as advanced medical protocols, surgical techniques, and stem cell therapy, are under active investigation.
Conclusions:
- Effective management of angina relies on a combination of current evidence-based therapies.
- Ongoing research into novel treatments promises to expand therapeutic options for patients with angina.
- Innovative approaches, including stem cell therapy, represent the future direction for angina treatment.
Related Concept Videos
Angina IV: Management
Angina V: Nursing Management
Coronary Artery Disease V: Interprofessional Care
Angina III: Clinical Manifestations and Assessment
Angina II: Classification
Atherosclerosis III: Management

