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[Persistent hyperplastic primary vitreous: case report and literature review]

R Grenga1, C Komaiha, G Bianchi

  • 1Dipartimento Organi di Senso, UOC Oftalmologia B, Università Sapienza, Policlinico Umberto I, Roma, Italia.

La Clinica Terapeutica
|January 16, 2014
PubMed

Insights

Persistent hyperplastic primary vitreous (PHPV) is a congenital eye anomaly. This case report details a unilateral PHPV presentation in an infant, highlighting key diagnostic findings.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Developmental Biology

Background:

  • Persistent hyperplastic primary vitreous (PHPV) is a rare congenital eye malformation.
  • It results from the failure of the primary vitreous and hyaloid vasculature to regress during fetal development.

Observation:

  • A 4-week-old infant presented with unilateral PHPV.
  • Clinical signs included microphthalmia and leukocoria in the affected right eye.

Findings:

  • Ocular examination revealed characteristic features of PHPV.
  • Echographic and magnetic resonance imaging (MRI) findings were crucial for diagnosis and differential diagnosis.

Implications:

  • Accurate and timely diagnosis of PHPV is essential for appropriate management.
  • Understanding the imaging findings aids in differentiating PHPV from other pediatric retinal and ocular anomalies.

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