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Serum vitamin d levels in Indian patients with multiple sclerosis

Radhakrishnan Suresh Kumar1, Sajid Syed2, Anandakuttan Anand Kumar2

  • 1Department of Neurology, Amrita Institute of Medical Sciences, Kochi, India ; G389, Panampilly Nagar, Kochi, 682036 India.

Indian Journal of Clinical Biochemistry : IJCB
|January 16, 2014
PubMed

Insights

This study found a significant trend of low vitamin D levels in Indian patients with multiple sclerosis (MS). Vitamin D deficiency is linked to increased MS risk, highlighting a potential area for further research in this population.

Area of Science:

  • Neurology
  • Endocrinology
  • Immunology

Background:

  • Low serum vitamin D levels are associated with an increased risk of multiple sclerosis (MS).
  • Limited data exists on vitamin D levels in the Indian population diagnosed with MS.

Purpose of the Study:

  • To investigate vitamin D levels in Indian patients diagnosed with multiple sclerosis.
  • To determine if vitamin D deficiency is prevalent in this demographic.

Main Methods:

  • The study included 26 patients diagnosed with MS using modified Mc Donald's criteria.
  • Serum 1,25 hydroxy vitamin D levels were measured via electro-chemiluminescence.
  • An age-matched control group of 202 individuals without MS was included for comparison.

Main Results:

  • A higher percentage of MS patients (76.9%) exhibited vitamin D levels below 20 ng/ml compared to the control group (65.5%).
  • The difference in vitamin D levels between the groups was statistically significant (p=0.019).
  • The findings indicate a trend towards lower vitamin D values in Indian MS patients.

Conclusions:

  • The study suggests a potential link between vitamin D deficiency and multiple sclerosis in the Indian population.
  • Further research is warranted to explore this association and its clinical implications.
Keywords:
Multiple sclerosisSunlightVitamin D

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