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Related Concept Videos

Appendicitis01:19

Appendicitis

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Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
29
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

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Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
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Cholecystitis01:20

Cholecystitis

29
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
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Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

35
Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
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Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
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Xanthogranulomatous appendicitis.

Kazunari Mado1, Takero Mazaki2, Akihiro Henmi3

  • 1Division of Digestive Surgery, Nihon University School of Medicine, Tokyo, Japan.

The Indian Journal of Surgery
|January 16, 2014
PubMed
Summary
This summary is machine-generated.

Xanthogranulomatous appendicitis is a rare condition that can mimic appendiceal mucocele on imaging. This case highlights the importance of histopathological diagnosis for this uncommon gastrointestinal disease.

Keywords:
AppendixXanthogranuloma

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Area of Science:

  • Gastroenterology
  • Pathology
  • Radiology

Background:

  • Xanthogranuloma is an uncommon condition.
  • Xanthogranulomatous appendicitis is particularly rare.
  • Appendiceal mucocele is a more common differential diagnosis.

Purpose of the Study:

  • To report a rare case of xanthogranulomatous appendicitis.
  • To highlight its radiological mimicry of appendiceal mucocele.
  • To emphasize the role of histopathology in diagnosis.

Main Methods:

  • Case presentation of a 78-year-old male.
  • Computed tomography (CT) imaging.
  • Surgical specimen histopathological examination.

Main Results:

  • CT revealed an irregular, multicystic mass near the cecum.
  • The mass mimicked appendiceal mucocele radiologically.
  • Histopathology confirmed xanthogranulomatous appendicitis.

Conclusions:

  • Xanthogranulomatous appendicitis can present as a diagnostic challenge.
  • Radiological findings can be mistaken for appendiceal mucocele.
  • Histopathological analysis is crucial for definitive diagnosis.