A rare case of hilar lymph node schwannoma

Schwannoma arising in a lymph node is an extremely rare primary mesenchymal tumor of the lymph node. Although intranodal schwannoma is benign, this lesion in a lymph node may be initially alarming and it may suggest a diagnosis of intranodal metastasis from a spindle cell tumor. Microscopic examination of tumor shows Antoni A areas, which are moderate to highly cellular areas of elongated cells arranged in fascicles, and Antoni B areas, which are hypocellular areas with myxoid and microcystic change. Tumor cell morphology is similar in both areas with elongated shape and regular oval nuclei. Immunohistochemistry report shows strong and diffuse positivity for S-100 which is consistent with Schwann cell origin. We report a rare case of intranodal schwannoma arising in the hilar lymph node with its clinical, light microscopic, and immunohistochemical findings.