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A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Intramuscular hemangiomas
Joseph M Wierzbicki1, Jeffrey H Henderson1, Mark T Scarborough2
1Primary Care Sports Medicine Fellowship, Department of Community Health and Family Medicine, University of Florida, Gainesville, Florida.
Context:
Intramuscular hemangiomas are common in the general population and often present at medical and surgical clinics. Unfortunately, unfamiliarity with these lesions has led to a high percentage of misdiagnoses, inappropriate workup, and unnecessary referrals.
Evidence Acquisition:
A literature search was performed using Medline, Embase, PubMed, and Cochrane. The relevant articles and referenced sources were reviewed for additional articles that discussed the epidemiology, pathophysiology, investigation, and management of intramuscular hemangiomas. Clinical experience from experts in orthopaedics, musculoskeletal pathology, and musculoskeletal radiology was compared. The selected case studies are shared cases of the authors.
Results And Conclusion:
The pathophysiology of these lesions is not completely understood, but much can be implied from their underlying vascular nature. Isolated lesions are benign tumors that never metastasize but tend to enlarge and then involute over time. Magnetic resonance imaging is the imaging modality of choice. If a systemic disorder or malignancy is not suspected or has been ruled out, conservative management is the treatment of choice for most intramuscular hemangiomas.
