Pharmacologic approaches to the aging athlete
John M Tokish1, Daniel C Derosa1
1Tripler Army Medical Center, Tripler AMC, Hawaii.
The anti-aging market is booming, but scientific evidence for many supplements is lacking. Clinicians must carefully evaluate products, distinguishing between scientific inquiry and marketing claims regarding aging interventions.
Area of Science:
- Gerontology and anti-aging research.
- Integrative and evidence-based medicine.
Background:
- Growing interest in supplements and therapies to counteract aging.
- The
Purpose of the Study:
- To review the scientific basis of popular anti-aging strategies.
- To guide clinicians in evaluating anti-aging products.
Main Methods:
- Review of scientific literature on anti-aging supplements and therapies.
- Assessment of evidence supporting hormone replacement and antioxidative strategies.
Main Results:
- Hormone replacement therapy (testosterone, growth hormone) shows mixed results.
- Antioxidative strategies have basic science support but lack clinical evidence.
- Many anti-aging products lack robust scientific validation and regulatory oversight.
Conclusions:
- Clinicians need to critically differentiate between scientific evidence and marketing in the anti-aging field.
- A rational approach to combating aging requires careful discernment of available data.
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