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Flow Cytometry Analysis of Murine Bone Marrow Hematopoietic Stem and Progenitor Cells and Stromal Niche Cells
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The bone marrow niche for haematopoietic stem cells

Sean J Morrison1, David T Scadden2

  • 1Howard Hughes Medical Institute, Children's Research Institute, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

Nature
|January 17, 2014
PubMed
Summary

The hematopoietic stem cell (HSC) niche in bone marrow is perivascular, involving stromal and endothelial cells. Further research is needed to fully define its cellular complexity and functional heterogeneity.

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