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Updated: May 4, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
Why is biopsy of suspected fungal lung lesions necessary?
Gabriele Kropshofer1, Bernhard Meister1, Cornelia Lass-Flörl2
1Department of Pediatrics, Anichstrasse 35, Innsbruck 6020, Austria.
Abstract:
The recognition of antifungal resistance is necessary for the choice of the appropriate treatment in patients with invasive fungal disease. In this case report, the need for a computed tomography-guided percutaneous lung biopsy of a suspected fungal lesion in a patient treated for acute leukemia is demonstrated. Detection of Amphothericin-B resistant Aspergillus flavus infection has prompted the switch in antifungal therapy, followed by full resolution of symptoms, completion of chemotherapy and remission since then.
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