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Updated: May 3, 2026
Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation
Published on: January 22, 2013
Imaging in occupational and environmental lung disease
Anna Rita Larici1, Manuela Mereu, Paola Franchi
1aDepartment of Radiological Sciences, Catholic University, 'A. Gemelli' Hospital, Rome bDepartment of Neuroscience and Section of Integrated Imaging and Radiological Therapies, University of Chieti, Chieti, Italy.
Imaging, particularly high-resolution computed tomography (HRCT), is crucial for diagnosing work-related and environmental lung diseases. Low-dose HRCT shows promise for screening exposed individuals, though further research is needed.
Area of Science:
- Pulmonology
- Radiology
- Occupational Medicine
Background:
- Work-related and environmental lung diseases are increasing.
- New antigens causing pulmonary responses are continually identified.
- Imaging findings associated with these conditions vary in specificity.
Purpose of the Study:
- To review the role of imaging in diagnosing occupational and environmental lung diseases.
- To describe classic and uncommon high-resolution computed tomography (HRCT) patterns.
- To update the literature on imaging in this field.
Main Methods:
- Literature review focusing on imaging findings.
- Emphasis on high-resolution computed tomography (HRCT) patterns.
- Analysis of prognostic significance of imaging findings.
Main Results:
- Recent literature on imaging is limited.
- HRCT appearance related to specific antigen exposure is a primary focus.
- Prognostic significance of imaging findings is also highlighted.
Conclusions:
- Imaging knowledge aids in identifying, characterizing, and following lung diseases.
- HRCT is key but limited by radiation exposure, especially in asymptomatic patients.
- Low-dose HRCT offers potential for screening and surveillance of exposed populations.
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