Transcatheter aortic valve replacement options for severe aortic stenosis in high-risk patients

Anita Lachell1, Lisa Henry

  • 1Anita Lachell, MSN, CRNP, RN Acute Care Nurse Practitioner, Heart and Vascular Institute, Division of Adult Cardiac Surgery, University of Pittsburgh Medical Center, Pennsylvania. Lisa Henry, DNP, CRNP, AACC Clinical Project Director, UPMC Heart and Vascular Institute, Pittsburgh, Pennsylvania.

Insights

Transcatheter aortic valve replacement offers improved quality of life for elderly patients with severe aortic stenosis. This evolving procedure is crucial for high-risk individuals when surgery is not an option.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Geriatric Cardiology

Background:

  • Calcific aortic stenosis is the most prevalent valvular disease in Western countries, primarily affecting individuals aged 70 and older.
  • Surgical aortic valve replacement, the traditional treatment, is often not feasible for elderly or high-risk patients.
  • The increasing geriatric population necessitates alternative treatment options for severe aortic stenosis.

Purpose of the Study:

  • To examine transcatheter aortic valve replacement (TAVR) as an evolving medical technology and procedure.
  • To highlight the importance of TAVR for high-risk and inoperable patients with severe aortic stenosis.
  • To emphasize the need for healthcare professionals to be informed about TAVR for competent care in an aging population.

Main Methods:

  • Review of international research and ongoing US studies on TAVR outcomes.
  • Focus on patient selection and team-based care approaches.
  • Examination of two major TAVR systems: Edwards SAPIEN valve (PARTNER trial) and Medtronic CoreValve (US Pivotal study).

Main Results:

  • International studies show promising results in improving quality of life, including reduced pain and enhanced functional status.
  • Research in the United States is expanding, with large trials underway.
  • The medical community anticipates the results of the PARTNER trial and US Pivotal study.

Conclusions:

  • Transcatheter aortic valve replacement demonstrates potential for significant quality of life improvements in select patient populations.
  • A multidisciplinary team approach, including specialized nursing coordination, is vital for successful TAVR programs.
  • Careful patient selection and thorough assessment by a trained valve clinic coordinator are crucial to minimize complications and ensure optimal outcomes.
Abstract

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
598
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
535
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
1.2K
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
632
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.6K
Mitral Stenosis IV: Nursing Management01:27

Mitral Stenosis IV: Nursing Management

A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
422