Related Experiment Video
Updated: May 3, 2026

12:04
Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
2.5K
Falls and comorbidity: the pathway to fractures
Terese Sara Høj Jørgensen1, Annette Højmann Hansen, Marie Sahlberg
11Department of Geriatric Medicine, Nykøbing-Falster Hospital, Denmark.
Scandinavian Journal of Public Health
|January 18, 2014
Summary
Nationwide data show declining hip and proximal humeral fractures in older adults. Reduced falls risk comorbidities likely explain this fracture incidence decrease, improving patient outcomes.
Area of Science:
- Gerontology
- Epidemiology
- Orthopedic Surgery
Background:
- Hip and proximal humeral fractures are significant causes of morbidity and mortality in older adults.
- Falls risk related comorbidities (FRICs) are common in this population and may influence fracture incidence.
Purpose of the Study:
- To analyze nationwide time trends in hip and proximal humeral fractures.
- To investigate the association between FRICs and fracture incidence.
- To examine mortality rates following these fractures.
Main Methods:
- Retrospective cohort study using Danish administrative registries (2000-2009).
- Inclusion of individuals aged 65+ with hip or proximal humeral fractures.
- Analysis of fracture and FRIC incidence, incidence rate ratios (IRRs), and all-cause mortality.
Main Results:
- A total of 89,150 hip and 48,581 proximal humeral fractures were recorded.
- Fracture incidence declined significantly in both males and females from 2000-2009.
- Incidences of FRICs also decreased, correlating with reduced fracture rates; elevated IRRs were observed for fractures in patients with FRICs.
Conclusions:
- The observed reduction in hip and proximal humeral fractures is likely attributable to a decrease in falls risk related comorbidities.
- These findings highlight the importance of managing comorbidities to prevent fractures in the elderly population.
Related Concept Videos
Fractures: Bone Repair
5.8K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
5.8K
Bone Disorders
8.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
8.0K
Flail Chest-I
1.2K
Overview of Flail Chest
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
1.2K
Essential Minerals for Bone Health
6.2K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
6.2K
Degenerative Disc Disease ll: Pathophysiology
30
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
30
Osteoclasts in Bone Remodeling
3.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.9K

