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A Murine Model of Vertical Sleeve Gastrectomy
Published on: December 18, 2017
Long-term improvements in pulmonary function 5 years after bariatric surgery
Stephen Hewitt1, Sjur Humerfelt, Torgeir T Søvik
1Department of Morbid Obesity and Bariatric Surgery, Department of Endocrinology, Obesity and Preventive Medicine, Medical Clinic, Oslo University Hospital, Aker, PO Box 4950, Nydalen, 0424, Oslo, Norway, stehewi@online.no.
Bariatric surgery significantly improves pulmonary function and reduces symptoms of asthma and obstructive sleep apnea syndrome (OSAS) 5 years post-operation. Weight loss and gender independently predict these positive respiratory outcomes.
Area of Science:
- Pulmonary Medicine
- Bariatric Surgery
- Obesity Medicine
Background:
- Obesity is a significant risk factor for reduced pulmonary function.
- Asthma and obstructive sleep apnea syndrome (OSAS) are prevalent comorbidities in obese individuals.
- The impact of bariatric surgery on respiratory health requires further investigation.
Purpose of the Study:
- To evaluate changes in pulmonary function (spirometry) 5 years after bariatric surgery.
- To assess the resolution of asthma and OSAS symptoms post-surgery.
- To identify factors associated with improvements in pulmonary function.
Main Methods:
- Prospective study involving 113 patients undergoing bariatric surgery (gastric bypass, duodenal switch, sleeve gastrectomy).
- Spirometry performed at baseline and 5-year follow-up.
- Recording of asthma and OSAS status and symptoms.
Main Results:
- Significant improvements in Forced Expiratory Volume in 1 second (FEV1) and Forced Vital Capacity (FVC) observed 5 years post-surgery.
- Weight reduction averaged 31% in women and 24% in men.
- 48% of asthma patients and 80% of OSAS patients reported symptom resolution.
- Gender and degree of weight loss were independent predictors of pulmonary function improvement.
Conclusions:
- Bariatric surgery leads to substantial and sustained improvements in pulmonary function.
- Significant symptom relief for asthma and OSAS is achieved post-bariatric surgery.
- These respiratory benefits occur despite age-related pulmonary decline.
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