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The En mutable system in maize : III. Transposition associated with mutational events.

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Summary
This summary is machine-generated.

The En transposable element in maize can cause mutations at the a1 locus, leading to color changes. Its movement (transposition) away from the a1 locus explains the high frequency of colorless and pale variants.

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Area of Science:

  • Genetics
  • Molecular Biology
  • Plant Science

Background:

  • The En transposable element system in maize influences gene expression at the a1 locus.
  • Somatic and germinal mutations are observed, resulting in pale, colorless, and purple phenotypes.

Purpose of the Study:

  • To investigate the mechanism of mutation at the a1 locus mediated by the En system.
  • To understand the role of En element transposition in generating mutable alleles.

Main Methods:

  • Analysis of maize genetic variants at the a1 locus.
  • Tracking the somatic and germinal mutation events.
  • Identifying the regulatory element (En) and its transposition behavior.

Main Results:

  • The En element at the a1 locus mediates somatic and germinal mutations to pale, colorless, and purple.
  • High frequencies of colorless and pale deviants correlate with early somatic mutation timing.
  • En element transposition away from the a1 locus is associated with colorless and pale deviants.
  • Transposition can occur to linked or unlinked sites, with a preference for sites near a1.

Conclusions:

  • En element transposition is the primary cause of mutable alleles at the a1 locus.
  • The timing and destination of En transposition influence mutation frequency and phenotype.
  • Transpositional behavior varies, suggesting system-specific and element-specific regulation.