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Updated: May 3, 2026
11:51
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
14.8K
Human bone reactions around implants with adverse interfacial bone strain over 20 years
Tonino Traini1, Carlo Mangano, Vittoria Perrotti
1Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Italy; Department of Dentistry, San Raffaele Hospital, Vita-Salute University, Milan, Italy.
Summary
Bone remodeling rate decreases with implant depth following fractures. Bone quality stabilizes around fractured implants, balancing mechanical and biological factors.
Area of Science:
- Biomaterials Science
- Orthopedic Research
- Dental Implantology
Background:
- Adverse interfacial bone strain can lead to bone damage and resorption.
- Fractured implants offer a unique model to study bone response to overstrain.
- Understanding bone morphology around fractured implants is crucial for improving implant design and patient outcomes.
Observation:
- The study analyzed bone morphology and morphometry around five retrieved human fractured implants.
- Microscopic investigation utilized transmitted brightfield and circularly polarized light.
- Key parameters assessed included total bone area, bone remodeling area, bone remodeling rate (BRR), and collagen fibers orientation (CFO).
Findings:
- The grouped samples exhibited a bone remodeling rate (BRR) of 51.9% (± 10).
- Transverse collagen fibers orientation (CFO) was measured at 13.0% (± 9.7).
- BRR significantly decreased with implant depth, from 58.1% (± 4.0) at level 1 to 40.4% (± 12.8) at level 2 (p=0.019).
Implications:
- Bone quality and level stabilize around fractured implants due to mechanical and biological interactions.
- The observed decrease in BRR with depth suggests that bone remodeling is depth-dependent around fractured implants.
- These findings contribute to understanding bone adaptation to implant failure and may inform future implant material and design strategies.
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