Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Signaling01:30

Bacterial Signaling

29.8K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
29.8K
Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

11.6K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
11.6K
Physical Methods for Controlling Microbial Growth: Radiation and Filtration01:26

Physical Methods for Controlling Microbial Growth: Radiation and Filtration

1.7K
Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
1.7K
Methods of Sterilization II: Chemical Methods01:30

Methods of Sterilization II: Chemical Methods

9.5K
In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
9.5K
Biofilms01:29

Biofilms

2.1K
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
2.1K
Hand hygiene01:23

Hand hygiene

5.2K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
5.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deposition of metal-organic frameworks within a porous protein crystal superstructure.

Journal of materials chemistry. B·2025
Same author

Anticoagulate the Circuit, Not the Patient: Nitric Oxide Reduces Thrombus Formation During Extracorporeal Carbon Dioxide Removal.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2025
Same author

Ex vivo evaluation of blood coagulation on endothelial glycocalyx-inspired surfaces using thromboelastography.

In vitro models·2025
Same author

Current Analytical Methods and Challenges for the Clinical Diagnosis of Invasive Pulmonary Aspergillosis Infection.

Journal of fungi (Basel, Switzerland)·2024
Same author

Copper(II) Ions Originating from CuBTC MOF Act as a Soluble Catalyst in the Friedländer Synthesis.

ACS applied materials & interfaces·2024
Same author

Achieving Biomedically Desirable Nitric Oxide Release from Glucose Monitor Surfaces Via a Cu-Based Catalyst Coating.

ACS applied bio materials·2024
Same journal

Bacterial spores as a modular platform for the production of amyloids for materials.

Trends in biotechnology·2026
Same journal

The oriGen case and Mexico's regulatory blind spots in genomic biobanking.

Trends in biotechnology·2026
Same journal

A caspase-3-activated protein expression system for apoptosis visualization and apoptosis-pyroptosis conversion to boost antitumor activity.

Trends in biotechnology·2026
Same journal

Over 4 months of ethylene production using solid-state photosynthetic cell factories.

Trends in biotechnology·2026
Same journal

Closing the nitrogen loop in groundwater with biohybrid technologies.

Trends in biotechnology·2026
Same journal

Engineering environmental bacteria for whole-cell PET hydrolysis and assimilation.

Trends in biotechnology·2026
See all related articles

Related Experiment Video

Updated: May 3, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

10.6K

Combating medical device fouling.

Jacqueline L Harding1, Melissa M Reynolds2

  • 1Department of Chemistry, Colorado State University, 1872 Campus Delivery, Fort Collins, CO 80523, USA.

Trends in Biotechnology
|January 21, 2014
PubMed
Summary
This summary is machine-generated.

Biomedical device biofouling is reduced by modifying surfaces with biomolecules. Strategies include changing surface properties and using peptides or nitric oxide (NO) to improve device integration.

More Related Videos

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting
08:53

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting

Published on: March 28, 2025

828
Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

25.4K

Related Experiment Videos

Last Updated: May 3, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

10.6K
Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting
08:53

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting

Published on: March 28, 2025

828
Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

25.4K

Area of Science:

  • Biomaterials Science
  • Surface Chemistry
  • Biomedical Engineering

Background:

  • Biomedical devices often face surface biofouling when interacting with the body, leading to issues like microbial adhesion and thrombotic agent buildup.
  • This biofouling stems from the foreign body response and nonspecific adhesion of undesirable substances to the device surface.

Purpose of the Study:

  • To review current strategies for developing biofouling-resistant surfaces for biomedical devices.
  • To explore how surface modifications and biomolecule incorporation can mitigate the foreign body response and enhance device integration.

Main Methods:

  • Summarizing approaches based on surface hydrophilicity, charge manipulation, and biomolecule functionalization.
  • Discussing drug elution techniques as a method to prevent biofouling.
  • Reviewing the use of specific biomolecules like peptides and nitric oxide (NO).

Main Results:

  • Biofouling-resistant surfaces can be achieved through tailored surface chemistry and the strategic use of biomolecules.
  • Incorporating peptides and NO shows promise in not only preventing fouling but also promoting better integration of devices with host tissues.
  • Reducing the foreign body response is key to minimizing device rejection and improving biocompatibility.

Conclusions:

  • Surface engineering is crucial for creating effective biofouling-resistant biomedical devices.
  • Biomolecule-based strategies, including peptides and NO, offer a dual benefit of preventing fouling and enhancing biological integration.
  • Further research into these strategies can lead to improved medical device performance and patient outcomes.