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The concept of normal weight obesity
Estefania Oliveros1, Virend K Somers1, Ondrej Sochor2
1Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
Progress in Cardiovascular Diseases
|January 21, 2014
Summary
Normal weight obesity, characterized by high body fat despite a normal body mass index (BMI), increases the risk of metabolic syndrome and mortality. Recognizing this condition is crucial for accurate health risk assessment.
Area of Science:
- Metabolic Health
- Obesity Research
- Cardiovascular Disease
Background:
- Normal weight obesity (high body fat percentage with normal BMI) is linked to metabolic dysregulation.
- This condition is associated with increased risks of metabolic syndrome, cardiometabolic dysfunction, and mortality.
- Coronary artery disease patients with normal BMI and central obesity face the highest mortality risk.
Purpose of the Study:
- To highlight the significance of normal weight obesity in risk stratification.
- To emphasize the need for an adiposity-based definition of obesity over a weight-based one.
Main Methods:
- Analysis of body composition and body mass index (BMI).
- Assessment of metabolic health markers.
- Evaluation of mortality risk in relation to adiposity patterns.
Main Results:
- Individuals with normal BMI and high body fat exhibit significant metabolic dysregulation.
- Normal weight obesity is a predictor of higher mortality risk.
- Central obesity in normal BMI individuals is linked to the highest mortality in coronary artery disease patients.
Conclusions:
- Normal weight obesity represents a critical, often overlooked, health risk.
- Adiposity-based definitions are superior for obesity risk stratification.
- Identifying individuals with normal weight obesity is essential for proactive health management.
Keywords:
BFBMIBody fat percentageCHDCVDCentral obesityDMHDLHFHOMAHTNHomeostasis Model AssessmentLDLMetabolically obese normal weightNWONormal weight obesityObesityWCWHOWHRWorld Health Organizationbody fatbody mass indexcardiovascular diseasecoronary heart diseasediabetes mellitusheart failurehigh-density lipoprotein cholesterolhypertensionlow-density lipoproteinnormal weight obesitywaist circumferencewaist-to-hip ratioMore Related Videos
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