[Angiogenic effect of colchicine]

The effect of colchicine on the microcirculatory vessels of eye perilimbal area was revealed in 2 groups of experimental rabbits. Colchicine was found to promote the growth of capillaries both during intravenous injections of colchicine solution and during local colchicine application as an ointment. The proper substance of cornea was also changed under the influence of colchicine. Changes in the ultrastructure of the capillary wall and endothelial cells forming the capillaries have been noted.