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MRI, enhanced CT, and FDG PET/CT in primary retroperitoneal mucinous cystadenocarcinoma

Aisheng Dong1, Zhijun Zhai, Yang Wang

  • 1From the Departments of *Nuclear Medicine, and †Pathology, Changhai Hospital, Second Military Medical University, Shanghai, China.

Clinical Nuclear Medicine
|January 22, 2014
PubMed

Insights

Primary retroperitoneal mucinous cystadenocarcinoma (PRMC) is a rare tumor. Imaging findings of a hypermetabolic retroperitoneal cystic lesion with normal ovaries on FDG PET/CT suggest PRMC.

Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Primary retroperitoneal mucinous cystadenocarcinoma (PRMC) is an exceptionally rare neoplasm.
  • This study details a unique case of PRMC, emphasizing diagnostic imaging findings.

Observation:

  • Abdominal MRI revealed a retroperitoneal cystic lesion with a mural nodule.
  • Enhanced CT demonstrated progressive enhancement of the mural nodule.
  • FDG PET/CT showed intense early uptake and increased SUVmax on delayed imaging.

Findings:

  • Histopathological analysis confirmed retroperitoneal mucinous cystadenocarcinoma.
  • Metastatic disease from the gastrointestinal tract or ovaries was ruled out.
  • The imaging characteristics were highly suggestive of PRMC.

Implications:

  • PRMC should be considered in the differential diagnosis of hypermetabolic retroperitoneal cystic lesions.
  • FDG PET/CT can be a valuable tool in identifying such rare tumors, especially when ovaries are normal.
  • This case highlights the importance of integrating imaging and histopathology for accurate PRMC diagnosis.

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