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Updated: May 3, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
[Social dysfunction of young persons with an ultra high risk of developing first-episode psychosis]
Background:
Schizophrenia is associated with severe social deficits. Social dysfunction is common in young persons with an ultra high risk (UHR) of developing a psychotic disorder.
Aim:
To present an overview of the literature on social deficits in the uhr phase, and to find out what role these deficits play in the prediction of a first psychotic episode.
Method:
We searched the literature using Psycinfo (covering the period from 1995 to January 2013) in order to locate articles relating to the role of social dysfunction in the UHR phase.
Results:
Young persons who meet one or more UHR criteria face more social constraints than the general population. Effect-sizes indicate differences ranging from medium to substantial (range Cohen's d = .63 - 4.18). Impairments in both social and role functioning contribute to the prediction of a first psychotic episode in UHR young persons.
Conclusion:
Research conducted on UHR adolescents shows, without exception, that functional limitations are already manifest in the phase preceding a clinical psychotic disorder. The experiencing of UHR symptoms is itself associated with (severe) social deficits that require treatment, regardless of whether the help-seeking uhr individual eventually develops a psychosis.
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