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Updated: May 3, 2026
Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
Published on: May 7, 2021
Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using
A Razetti1, R O Farías2, S I Thorp3
1Universidad Favaloro, FICEN, Av. Belgrano 1723 (1093), C.A.B.A., Buenos Aires, Argentina.
Abstract:
A model of multiple lung metastases in BDIX rats is under study at CNEA (Argentina) to evaluate the feasibility of BNCT for multiple, non-surgically resectable lung metastases. A practical shielding device that comfortably houses a rat, allowing delivery of a therapeutic, uniform dose in lungs while protecting the body from the neutron beam is presented. Based on the final design obtained by numerical simulations, the shield was constructed, experimentally characterized and recently used in the first in vivo experiment at RA-3.
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