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Updated: May 3, 2026

Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags
Published on: January 17, 2019
Redox-driven host-guest interactions allow the controlled release of captured cells on RGD-functionalized surfaces
Dhruv Thakar1, Liliane Coche-Guérente, Michaël Claron
1Université Grenoble Alpes, Département de Chimie Moléculaire, CNRS, UMR 5250, FR 2607, 570 rue de la chimie, B. P. 53, 38400 Grenoble (France).
Abstract:
A quartz crystal microbalance technique with dissipation monitoring and a complementary optical microscopy technique were used for monitoring the capture and release of specific cells on a surface displaying a bifunctional molecular device, composed of a molecular scaffold endowed with the cell recognition property of an RGD ligand and a β-CD/Fc redox-switchable system.

