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Limitations of adaptive clinical trials

Marc Buyse1

  • 1From the International Drug Development Institute, Houston, TX; Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Diepenbeek, Belgium.

American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting
|January 24, 2014
PubMed
Summary

Adaptive designs enhance clinical research flexibility by allowing trial adjustments based on interim data. These adaptive strategies are most beneficial in early-phase trials due to limited initial data.

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