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Updated: May 3, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
N-(2-Oxo-2,3,4,5,6,7-hexa-hydro-1H-azepin-3-yl)cyclo-hexa-necarboxamide
1Suzhou University Experimental Material Supply Center, Suzhou 215123, People's Republic of China.
Abstract:
In the title compound, C13H22N2O2, both the six-membered ring and the seven-membered lactam ring adopt chair conformations. In the crystal, mol-ecules are linked by pairs of N-H⋯O hydrogen bonds between inversion-related lactam rings into centrosymmetric dimers with an R 2 (2)(8) graph-set motif. Further N-H⋯O hydrogen bonds link the molecules into [100] chains.
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